Eleanore Chuang

Department of Tropical Medicine, Medical Microbiology and PharmacologyChuang
John A. Burns School of Medicine, University of Hawaii at Manoa
651 IIalo Street, Bioscience Building 320
Honolulu, Hawaii 96813
Email: eleanore@hawaii.edu

Personal Statement
Before arriving in Honolulu, I worked as a Biologist at NIH. At the Clinical Center’s Nuclear Medicine Department, we analyzed radiation-induced DNA damage and developed sequence-specific gene targeting with triplex-forming oligonucleotides. At NIAID’s Laboratory of Cellular and Molecular Immunology, we investigated CD4+ T cell activation and tolerance in a mouse model of autoimmune disease. After twelve years at NIH, I enrolled in the Ph.D. program in Tropical Medicine at the University of Hawaii in order to transition to more human disease-focused research.

Education
Harvard University.  1998, B.S. – Biological Science
University of Hawaii at Manoa. 2012 – present, Ph.D. candidate – Tropical Medicine

Experience
2007-2008 – Biologist – Nuclear Medicine Department, Clinical Center, NIH
2007-2012 – Biologist – Laboratory of Cellular and Molecular Immunology, NIAID, NIH

Interests & Hobbies
After completing the five-month AIDS Marathon Training Program, I finished the 2003 Mardi Gras Marathon in New Orleans, raising funds for the Whitman-Walker Clinic, which provides medical and support services to HIV/AIDS patients in the Washington, D.C. metropolitan area.  I also tutored middle school students in Kensington, MD through the SPARK program.  Other interests include travel, cultural arts, theater, and dance.  I am currently a Student Affiliate with the East-West Center.

Selected publications and presentations
Singh NJ, Chuang E, Augustine M, Jung M Schwartz RH.Density dependent re-tuning of autoreactive T cells alleviates their pathogenicity in a lymphopenic environment. (manuscript pending)

Kugler D, Chuang, EJ, Schwartz RN. The transcriptional landscape of adaptively tolerant T cells. Poster presentation. 2008.

Panyutin IV, Panyutin IG, Chuang EJ, Neumann RD. Effect of ionizing radiation on differentiation of human embryonic stem cells in culture.  Poster presentation. 2007.

He Y, Panyutin IG, Panyutin IV, Panyutin, Chuang EJ, Demidov VV, Neumann RD.  Peptide Nucleic Acid as Radiopharmaceutical for Gene-Specific Radiotherapy and Imaging. Poster presentation. 2002.

Haley MA, Panyutin IV, Panyutin IG, Chuang EJ, Neurmann RD. Molecular cloning of a Triplex-Forming Sequence to a Plasmid Vector. Poster presentation. 2001.

Haley M, Chuang E, Panyutin IV, Panyutin IG, Neumann RD. In Vitro Sequence Specific Gene Targeting by Triplex Forming Oligonuceotides. Poster presentation. 2000.