Department of Tropical Medicine, Medical Microbiology and Pharmacology
John A. Burns School of Medicine, University of Hawaii at Manoa
651 Ilalo Street, Bioscience Building 320-33
Honolulu, Hawaii, 96813
As an undergraduate I became interested in the complex interactions between pathogens and their hosts leading to the development of serious disease. I joined the Department of Tropical Medicine, Medical Microbiology and Pharmacology because of their unique interdisciplinary approach to the study of infectious disease pathogenesis. I am currently a PhD candidate, working with Dr. Saguna Verma to understand the early innate immune signaling pathways that lead to the detection of West Nile virus and the subsequent induction of inflammatory responses that lead to an opening the blood-brain barrier and encephalitis.
Western Washington University. B.S. w/honors, 2009 – Biochemistry
University of Hawaii at Manoa. M.S., 2011 – Tropical Medicie
University of Hawaii at Manoa. Ph.D. candidate, 2012 – present-Tropical Medicine
2006-2009 – Peer tutor in chemistry, mathematics and biology, Tutoring Center, Western Washington University
2008-2009 – Undergraduate Research Assistant, Department of Chemistry, Western Washington University
2009 – Teaching Assistant, University of Hawaii at Manoa
2009-present – Graduate Research Assistant, Department of Tropical Medicine, Medical Microbiology and Pharmacology, University of Hawaii at Manoa
Interests and Hobbies
I enjoyed the opportunity to mentor students in multiple settings as both a peer tutor and a teaching assistant, learning valuable skills in the process. I have also collaborated with fellow graduate students as serving as both the secretary and subsequently the president of the Hawaii Student Chapter of the American Society of Microbiology. My hobbies include hiking, biking, reading and beading.
Selected publications and presentations
Roe K, Kumar M, Lum S, Orillo B, Nerurkar VR, Verma S. (2012). In vivo West Nile virus infection modulates the markers of blood-brain barrier integrity. Journal of General Virology. 1193–1203.
Kumar M, Roe K, Nerurkar PV, Namekar M, Orillo B, Verma S, Nerurkar VR. (2012) Increased mortality and impaired virus clearance and immune response in type II diabetic mice infected with West Nile virus. PlosOne. 7(8), e44682.
Roe K, Kumar M, Orillo B, Maruve DA, Gale M, Nerurkar VR, Verma S. Inflammasome sensor apoptosis-associated spec-like protein containing CARD (ASC) restricts West Nile virus (WNV) infection and spread to the central nervous system. Poster Presentation. 2012 Biomedical sciences symposium. John A Burns School of Medicine, University of Hawaii at Manoa, Honolulu, April 17-18, 2012.